Patient Stories — Real Outcomes at Regeneris Therapy

In their words

“I'm 58 and was looking at a double knee replacement. My orthopedic surgeon in Phoenix had already filled out the paperwork. He's a friend, and he actually said — off the record — 'If you have the money and the time, try stem cells first. I wouldn't put my own knees through replacement at your age unless I had to.' That stuck with me. I flew to Cancun a month later. The team did MRI review, weight-bearing X-rays, and a 90-minute physical exam before they agreed to treat me. I appreciated that they almost talked me out of it — they were very direct that grade III is the upper edge of where they expect a good response, and grade IV bone-on-bone is not a candidate. Right knee was the bad one. After the first infiltration I noticed less stiffness in the morning within about 6 weeks. The pain on stairs took longer — maybe 4 months. After the second session and rehab, I'm walking 3 to 5 miles a day, sleeping through the night, and I cancelled the surgery. I won't say it's 'cured' — I still feel it on long hikes — but I bought myself maybe a decade.”

In their words

“Tengo lupus desde los 32. Llevaba ya casi diez anos con brotes cada 3 o 4 meses — articulaciones, fatiga, erupciones, y dos hospitalizaciones por nefritis. Mi reumatologa fue quien me menciono que existian protocolos con celulas madre en Mexico bajo COFEPRIS y me dio el contacto de Regeneris. Lo primero que me dijeron en consulta fue que ellos NO iban a sustituir a mi reumatologa — que iban a trabajar a la par. Eso me dio confianza, porque no queria abandonar mi tratamiento. La primera infusion fue tranquila, en sillón, con suero, como una IV larga. Lo que mas note fue, despues de unas 8 semanas, que la fatiga bajo. Antes me costaba bañarme y vestirme en el mismo dia. Ahora puedo trabajar 6 horas, hacer ejercicio ligero, y dormir bien. Mi reumatologa pudo bajarme la prednisona de 10mg a 5mg. Los anticuerpos anti-DNA bajaron pero siguen positivos. Sigo con lupus. No me curaron. Pero la calidad de vida es otra.”

In their words

“I started losing hair at 28. By 36 I was a Norwood IV with serious crown recession. I'd done minoxidil and finasteride for two years and they slowed the loss but I wasn't growing anything back. My derm in California suggested PRP and I priced it locally — about $4,500 for four sessions, no exosomes. I priced Regeneris and got PRP plus exosomes plus the consult for less. I went down for a long weekend, did the first session, and they prescribed a take-home topical for between sessions. By month 4 I could see baby hairs on the crown in the mirror. By month 8 my partner pointed out the density before I did. I'm not regrowing the temples — they told me up front the frontal hairline is the hardest area and to keep expectations modest there. But the crown is denser, and I'm not losing more. Still on the finasteride from home.”

In their words

“I'll keep this brief out of respect for myself and my wife. I'm 47. After two years of declining function and 18 months of escalating PDE5 doses that worked less and less, I was at the end of conventional options short of injections, which I was not willing to use long-term. A urologist in Madrid mentioned regenerative options were available abroad. I researched several clinics and chose Regeneris because they had a published protocol, not just a website. The treatment itself was uncomfortable but quick — they used local anesthesia and the team was professional and matter-of-fact, which I appreciated. By the third session I noticed spontaneous nocturnal function returning. By month 4 I was off PDE5 entirely on most occasions. My IIEF-5 score went from 11 (moderate ED) to 22 (no ED) at the 6-month follow-up. I will not pretend it cured underlying cardiovascular risk factors — they sent me back to my GP for those — but it restored function and I am grateful.”

In their words

“I was diagnosed with RRMS at 36. I've been stable on ocrelizumab — no new lesions in three years on MRI. But the symptoms I lived with were fatigue and stiffness in both legs by 2 pm every day. Standard MS care doesn't really treat that residual disease burden. My neurologist was honest: 'There is nothing more I can do for fatigue.' She told me she could not endorse stem cell therapy because it lacks long-term RCT data in MS, but she also said: 'If you go, go somewhere serious, send me the protocol, and do not stop your ocrelizumab.' I sent the Regeneris protocol to her. She read it and gave me the OK with the caveat that this was experimental. Six months after my second infusion, my afternoon energy is meaningfully better — I can work past 3 pm. The leg tightness is the same. I do not know if the IVs caused the energy change or if it was placebo or coincidence. Neither does my neurologist. But it is real to me, and my MRI in November showed no new lesions, which she was relieved about.”

In their words

“I got COVID in February 2024. I never recovered. By the time I called Regeneris in May 2025, I could not work a full day. I'd shower in the morning and then need to lie down before I could put on clothes. Two long-COVID clinics in the US had run labs and said everything looked 'within normal range' and offered me low-dose naltrexone, which helped a little. I did not expect a miracle. I told them so on the consult call. They told me they could not promise anything either — long COVID has no validated regenerative protocol, and they would treat me on the hypothesis of mitochondrial dysfunction and post-viral immune dysregulation, not on proven efficacy. I appreciated the honesty. I did the IV series first. The NAD infusions were uncomfortable — I'd been warned. By the end of the 10-IV series, my brain fog was meaningfully clearer. Post-exertional crashes still happened but they were less severe. After the MSC infusion in September, I had a noticeable lift around week 6. I am still not 100% — maybe 75% of pre-COVID. But I am working again and I can grocery shop without paying for it the next day.”

In their words

“I'd been dealing with sciatica down my left leg for almost two years. I'd done physio, three rounds of epidural steroid injections, and an L4-L5 microdiscectomy was the next recommendation from my Canadian spine surgeon. He was actually the one who said — and I quote — 'If I were you, before I let me operate, I'd look into regenerative options in Mexico or Europe.' I appreciated that more than I can say. I flew to Cancun for a single procedure. They did an MRI review and a fresh ultrasound assessment before going ahead — they declined to treat the same day; they wanted 48 hours to plan the injection trajectory. The procedure itself was outpatient, under local. I walked out two hours later. For the first month I felt worse — they warned me this was common with inflammation flares. By month 3 the sciatica was meaningfully better. By month 6 it was 80% gone. I am back at work full-time, I'm doing my home gym routine again, and I have not scheduled the surgery. I still get a flicker of pain when I sit too long. It is not gone. But it is livable, and that's what I wanted.”

In their words

“I am a 62-year-old retired executive. I came to Regeneris three years ago not because I was sick but because I wanted to be the version of myself at 70 that most of my peers were at 55. I'm a quantified-self type — I track biological age via TruDiagnostic, I do annual labs, full-body MRI, hsCRP, ApoB, all of it. They were one of the few clinics I interviewed that did not oversell. The doctor told me on the first call that 'longevity medicine' is still building its evidence base and that I should expect modest, incremental changes — not a 20-years-younger transformation. Three years in, my biological age has dropped from 58.4 to 53.1 on TruDiagnostic (DunedinPACE acceleration slowed from 1.04 to 0.96). My VO2max is up, my fasting insulin is down, my hsCRP normalized. My skin — that's where my wife notices the most — is better than it was at 58. I cannot prove the stem cells did any of this versus the lifestyle changes I made in parallel. They tell me that too. But the trend is real, the labs are real, and I plan to continue.”

In their words

“I'm a former collegiate baseball pitcher now playing recreational tournaments. I tore my rotator cuff in April 2024 throwing a slider. I did four months of PT and was still at 60% velocity and full of pain. My ortho in Texas offered cortisone and 'we'll see' — I'd had two cortisone shots already and I knew that wasn't building tissue. A teammate had been to Regeneris for a similar injury two years prior and had a good outcome. The eval was thorough — ultrasound dynamic exam, MRI re-read, full kinetic chain assessment. They told me up front that with a partial tear and intact tendon footprint I was a good candidate, but that if my labrum was the real driver the PRP wouldn't help and I'd be back to square one. Single injection. I followed the rehab protocol religiously — they emailed it to my physical therapist back home. Three months later I was back on the mound at 90% velocity. Six months later I was throwing pain-free and full bullpens. I'm not pitching pro again, but I'm playing in my Sunday league and that's all I wanted.”

In their words

“Soy diabetico tipo 2 desde los 46. Llevaba diez anos con A1c entre 8 y 9 a pesar de tomar metformina, glipizida y sitagliptina. Mi endocrinologo me iba a empezar insulina. Mi esposa investigo opciones y encontro Regeneris. Lo primero que me dijeron fue que NO tratan diabetes tipo 1, y que para tipo 2 no es una cura — es coadyuvante, y solo si mi endocrinologo seguia llevando mi manejo. Le hablaron a mi endocrinologo y revisaron el caso juntos. Mi endocrinologo decidio anadir semaglutida (eso lo recetó EL, no Regeneris) y autorizo las infusiones IV como complemento. Entre las dos infusiones, la semaglutida, y bajar 14 kilos siguiendo el plan nutricional, mi A1c bajo de 8.4 a 6.2. Mi endocrinologo redujo la glipizida. Sigo con metformina y semaglutida. No estoy 'curado' — sigo siendo diabetico — pero mi A1c esta controlado por primera vez en una decada. Lo importante es que ellos no se atribuyeron todo el credito. Me dijeron claramente que la semaglutida y la baja de peso probablemente hicieron mas que las celulas madre. Eso me dio mas confianza, no menos.”

In their words

“I have lived with fibromyalgia since I was 36. Twelve years. I have done every conventional treatment — duloxetine, pregabalin, low-dose naltrexone, six therapists, two sleep studies, three rheumatology consults. Some helped a little. Nothing changed the underlying pain floor. I went to Regeneris with very low expectations. The intake doctor was the first physician in twelve years who said to me, in plain English, 'Fibromyalgia has no proven regenerative cure. What we can try to do is reduce your central sensitization burden, restore some sleep, and improve mitochondrial function. We do not know how much of that will translate to less pain for you.' I appreciated being treated like a thinking adult. Ten months on, my widespread pain is down from a baseline 6/10 to a baseline 4/10. My sleep is meaningfully better — I'm getting 6-7 hours instead of 4-5. My fatigue is improved but still significant. I am not 'better' in the sense of being cured. I am 'better' in the sense of being able to work full days and have weekends with my kids. Some days are still bad. They warned me they would be.”

In their words

“We are publishing this story because Regeneris asked permission to publish it, and I said yes — because I think other patients deserve to hear from someone like me, not just from the patients who got the result they wanted. I am 67. I had moderate bilateral hip osteoarthritis. I came to Regeneris after my brother-in-law had a great outcome with his knees there. The intake doctor was honest with me. She told me that hip OA tends to respond less than knee OA in their data, and that older patients respond less than younger ones. She gave me her best estimate of about a 55-60% chance of meaningful response, and was clear that the alternative — eventual hip replacement — has a more established outcome. I chose to try. I did the first session in January. By six months I had not noticed any meaningful change in pain or function. I told them that on a phone follow-up. They suggested a second session with the caveat that if I had no response to the first, the odds of response to the second were lower. I did the second session anyway. Six months later, still no meaningful change. I have since had my left hip replaced, and the right is scheduled. I do not regret trying — I appreciate having had the honest framing. I do not feel like I was sold something I shouldn't have been. The protocol just did not work for me. Not every protocol works for every patient. I think people considering these treatments should know that.”